METHOD FOR PREVENTING INFLUENZA BY COMBINED APPLICATION OF INTERFERON GAMMA AND INACTIVATED ANTI-INFLUENZA VACCINE Russian patent published in 2015 - IPC A61K39/145 A61K38/21 A61P31/16 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to immunology, and can be used for preventing influenza. That is ensured by combined single administration of cytokine that is ensured by interferon gamma, and an inactivated anti-influenza vaccine. Interferon gamma is administered intermuscularly or subcutaneously in a dose of 0.5 ml 100,000 International Units±10% into the upper one-third of one shoulder; then the inactivated anti-influenza vaccine 0.5ml based on vaccine influenza viral strains (H5N1) Orniflue containing heamagglutinin in a minimum dose of 15 mcg/dose for this vaccine is administered intramuscularly into the upper one-third of the other shoulder.

EFFECT: method enables increasing immunogenicity and protective activity of the vaccine ensured by single vaccination and reducing side effects on the antigen by the immune response modulation.

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