INJECTION OR INFUSION SOLUTION OF L-ARGININE SALT OF 5-METHYL-6-NITRO-1,2,4-TRIAZOLO[1,5-a] PYRIMIDIN-7-ONE MONOHYDRATE FOR THERAPY OF INFLUENZA AND OTHER VIRAL INFECTIONS Russian patent published in 2016 - IPC A61K9/08 A61K31/53 A61P31/12 A61P31/16 

FIELD: medicine.

SUBSTANCE: disclosed are compositions for injection and infusion solutions of antiviral preparation wide range of action - L-arginine salt of 5-methyl-6-nitro-1,2,4-triazolo[1,5-a]pyrimidin-7-one monohydrate, including auxiliary components. Infusion and injection solutions of L-arginine salt of 5-methyl-6-nitro-1,2,4-triazolo[1,5-a]pyrimidin-7-one monohydrate are based on use of solubilisers of Glutamine type, which increases solubility of main medicinal component and its bioavailability in tissues in a vascular bed. Introduction of Glutathione and Carnosine is linked with their ability to stabilise cell metabolism of Z-arginine salt of 5-methyl-6-nitro-1,2,4-triazolo[1,5-a]pyrimidin-7-one monohydrate and increasing viability of infected cells.

EFFECT: injection and infusion forms of antiviral preparation based on L-arginine salt of 5-methyl-6-nitro-1,2,4-triazolo[1,5-a]pyrimidin-7-one monohydrate are intended for treating severe forms of viral infections in accordance with pharmacological profile of antiviral activity and primarily complicated by influenza.

2 cl, 2 ex, 2 tbl, 1 dwg