FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to compounds providing the targeted drug delivery to CD1d receptor cells and inducing an immune response as compared to an antigen, to based compositions and to a method using them applicable in medicine, of formula
,
wherein R1, R2, R3, and R4 represents hydrogen; R6 represents -(CH2)xCH3, x represents an integer from 20 to 25, or -(CH2)xCH=CH(CH2)yCH3, x, y and z independently represent an integer from 1 to 14, R5 is described by formula
,
wherein R8 represents hydrogen, R7 represents C3-C15 alkyl; X represents N; X represents -(CH2)t, wherein t is an integer within 3-10; Z represents a peptide antigen.
EFFECT: prepared are the new biologically active compounds effective for simulating the immune response.
12 cl, 6 dwg, 5 ex
Authors
Dates
2015-04-20—Published
2008-11-07—Filed