METHOD OF TREATING PERIODONTITIS AND ORAL MUCOSAL DISEASES ASSOCIATED WITH HELICOBACTER INFECTION, AND METHOD FOR USING IT Russian patent published in 2015 - IPC A61K31/29 A61K31/695 A61K47/30 A61P1/02 

Abstract RU 2549445 C1

FIELD: medicine.

SUBSTANCE: agent for treating inflammatory periodontal and oral mucosal diseases associated with Helicobacter infection contains silicone glycerohydrogel of Si(C3H7O3)4·6C3H8O3·24H2O and bismuthate tripotassium dicitrate of formula [HOC(CH2COO)2COO]2K3Bi in the following proportions, wt %: bismuthate tripotassium dicitrate 1.0-2.5; silicone glycerohydrogel - the rest up to 100. The method of treating inflammatory periodontal and oral mucosal diseases consists in a combination of systemic standard anti-Helicobacter therapy and a local effect of the above agent on the involved region. Particularly, treating periodontitis is ensured by applying the agent on the gingival surface and introducing it into the gingival pockets once a day for 10 min; the therapeutic course makes 5-6 days. The oral mucosal diseases are treated by applying the agent 0.1 mm thick with a glass spatula on the involved oral mucosa 2 times a day; the therapeutic course is 12 days.

EFFECT: formulation of the agent provides achieving the high therapeutic effect; the dosage form is easy to be applied locally.

4 cl, 2 dwg, 1 tbl, 2 ex

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Authors

Orlova Ekaterina Sergeevna

Bragin Aleksandr Vital'Evich

Akmalova Gjuzel' Maratovna

Khonina Tat'Jana Grigor'Evna

Shadrina Elena Vladimirovna

Nagaeva Marina Olegovna

Korotkova Elena Evgen'Evna

Dates

2015-04-27Published

2014-02-12Filed