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2 549 574

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IPC

C07D493/04(2006-01-01)

A61K31/4192(2006-01-01)

A61P29/00(2006-01-01)

(21) (22)

Application

2014109814/04, 2014-03-13

(24)

Start date

2014-03-13

(22)

Actual filing date

2014-03-13

(45)

Published

2015-04-27

(72)

Inventor

Shul'Ts Ehl'Vira EhduardovnaLipeeva Alla ViktorovnaDolgikh Margarita PetrovnaMorozova Ekaterina AleksandrovnaTolstikova Tat'Jana Genrikhovna

(73)

Holder

Federal'Noe Gosudarstvennoe Bjudzhetnoe Uchrezhdenie Nauki Novosibirskij Institut Organicheskoj Khimii Im. N.N. Vorozhtsova Sibirskogo Otdelenija Rossijskoj Akademii Nauk So Ran)

(E)-2-(4-{ [3-(2,4-DIMETHOXYPHENYL)ACRYLAMIDO]METHYL} -1H-1,2,3-TRIAZOLE-1-YL)-2-ISOPROPYL-9-(4-METHYL PIPERAZINE-1-YL)-3,7-DIOXO-3,7-DIHYDRO-2H-FURO[3,2-g]CHROMEN, HAVING ANALGESIC ACTIVITY Russian patent published in 2015 - IPC C07D493/04 A61K31/4192 A61P29/00

Abstract RU 2549574 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to a low-toxic (E)-2-(4-{[3-(2,4-dimethoxyphenyl)acrylamido]methyl}-1H-1,2,3-triazole-1-yl)-2-isopropyl-9-(4-methyl piperazine-1-yl)-3,7-dioxo-3,7-dihydro-2H-furo[3,2-g]chromen of formula (I) , having the analgesic activity in the test "acetic acid-induced writhing". The said property enables to use this compound in medicine.

EFFECT: compound of formula I is prepared from furocoumarin peucedanine contained in the plant Peucedanum morisonii.

1 tbl, 5 ex

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RU 2 549 574 C1

Authors

Shul'Ts Ehl'Vira Ehduardovna

Lipeeva Alla Viktorovna

Dolgikh Margarita Petrovna

Morozova Ekaterina Aleksandrovna

Tolstikova Tat'Jana Genrikhovna

Dates

2015-04-27—Published

2014-03-13—Filed