FIELD: chemistry.
SUBSTANCE: invention relates to organic chemistry and specifically to pyrazolo[3,4-b]pyridine compounds and a method for production thereof. Described are 2-(6-aryl-4-aroyl-3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridin-5-yl)-2-oxo-N-arylacetamides of formula 
,
where Ar1=Ph, C6H4Me-4; Ar2=Ph, C6H4Me-4, C6H4Br-4, and a method for production thereof by boiling 1-aryl-4,5-diaroyl-1H-pyrrole-2,3-diones with 5-amino-3-methyl-1-phenyl-1H-pyrazole in a medium of inert aprotic solvent.
EFFECT: obtaining novel compounds which can be used as primary products for synthesis of novel heterocyclic systems and in pharmacology as potential medicinal agents with analgesic activity.
4 cl, 1 tbl, 3 ex
| Title |
Year |
Author |
Number |
| 1,6'-DIARYL-3-AROYL-4-HYDROXY-1',3'-DIMETHYLSPIRO[PIRROLE-2,5'-PYRROLO[2,3-d]PYRIMIDINE]-2',4',5(1H,1'H,3'H)-TRIONES AND METHOD FOR PRODUCTION THEREOF |
2012 |
- Silajchev Pavel Sergeevich
- Maslivets Andrej Nikolaevich
- Makhmudov Ramiz Ragibovich
|
RU2502738C2 |
| METHYL 3-METHYL-5-[2-(4-ARYLAMINO)-2-OXOACETYL]-1,6-DIPHENYL-1H-PYRAZOLO[3,4-b]PYRIDINE-4-CARBOXYLATES AND METHYL 3-METHYL-5-[2-(4-ARYLAMINO)-2-OXOACETYL]-6-STYRYL-1-PHENYL-1H-PYRAZOLO[3,4-b]PYRIDINE-4-CARBOXYLATES AND METHOD FOR PREPARING THEM |
2012 |
- Maslivets Andrej Nikolaevich
- Bubnov Nikolaj Vladimirovich
- Silajchev Pavel Sergeevich
- Filimonov Valerij Olegovich
- Makhmudov Ramiz Ragibovich
|
RU2495039C1 |
| INTERMEDIATE PRODUCTS - METHYL 7-ARYL-4, 9-DIAROYL-3-HYDROXY-1-(2-HYDROXYPHENYL)-2,6-DIOXO-1, 7-DIAZASPIRO[4,4]NONE-3, 8-DIENE-8-CARBOXYLATES; METHYL 6, 9-DIARYL-11-AROYL-2-(O-HYDROXYPHENYL)-3, 4,10-TRIOXO-7-OXA-2, 9-DIAZATRICYCLO[6.2.1.0]UNDEC-5-ENE-8-CARBOXYLATES; METHOD OF PRODUCING METHYL 6, 9-DIARYL-11-AROYL-2-(O-HYDROXYPHENYL)-3, 4, 10-TRIOXO-7-OXA-2, 9-DIAZATRICYCLO [6.2.1.0]UNDEC-5-ENE-8-CARBOXYLATES; METHYL 11-BENZOYL-2-O-HYDROXYPHEHYL-3, 4, 10-TRIOXO-9-P-TOLYL-6-PHENYL-7-OXA-2, 9-DIAZATRICYCLO [6.2.1.0]UNDEC-5-ENE-8-CARBOXYLATE HAVING ANTIMICROBIAL ACTIVITY |
2008 |
- Racheva Nadezhda L'Vovna
- Maslivets Andrej Nikolaevich
- Aleksandrova Galina Arsent'Evna
|
RU2383550C1 |
| N-ARYL-2,3-DIAROYL-8,10-DIMETHYLPYRIDO[2',3',3,4]PYRAZOLO[1,5-α]PYRIMIDINE-4-CARBOXAMIDE AND METHOD FOR PREPARING THEM |
2012 |
- Silajchev Pavel Sergeevich
- Maslivets Andrej Nikolaevich
|
RU2478640C1 |
| METHOD OF PRODUCING METHYL 1,7-DIARYL-9-AROYL-4-BENZOYL-3-HYDROXY-2,6-DIOXO-1,7-DIAZASPIRO[4,4]NONE-3,8-DIENE-8-CARBOXYLATES, EXHIBITING ANALGESIC ACTIVITY |
2013 |
- Denislamova Ekaterina Sergeevna
- Dubovtsev Aleksej Jur'Evich
- Makhmudov Ramiz Ragibovich
- Maslivets Andrej Nikolaevich
|
RU2537999C1 |
| ETHYL 1,6-DIARYL-4-AROYL-3-HYDROXY-2-OXO-8-PHENYL-1,7-DIAZASPIRO[4,4]NONA-3,6,8-TRIEN-9-CARBOXILATES AND METHOD OF THEIR OBTAINING |
2011 |
- Silajchev Pavel Sergeevich
- Makhmudov Ramiz Ragibovich
- Maslivets Andrej Nikolaevich
|
RU2467010C1 |
| METHYL 4-ARYL-1-(1,5-DIMETHYL-3-OXO-2-PHENYL-2,3-DIHYDRO-1H-PYRAZOL-4-YL)-2,3-DIOXO-2,3,5,10 -TETRAHYDROBENZO[b]PYRROLO[2,3-e][1,4]DIAZEPINE-10a(1H)-CARBOXYLATES EXHIBITING ANALGESIC ACTIVITY, AND METHOD OF THEIR PREPARATION |
2022 |
- Denislamova Ekaterina Sergeevna
- Liadov Vadim Aleksandrovich
- Makrushin Dmitrii Evgenevich
- Maslivets Andrei Nikolaevich
- Malysheva Kseniia Olegovna
- Triandafilova Galina Andreevna
- Solodnikov Sergei Iurevich
|
RU2811413C1 |
| METHYL 11-ARYL-12-AROYL-9-HYDROXY-4,6-DIMETHYL-3,5,10-TRIOXO-4,6,8,11-TETRAAZATRICYCLO[7,2,1,0]DODEC-2(7)-ENE-1-CARBOXYLATES AND SYNTHESIS METHOD THEREOF |
2008 |
- Denislamova Ekaterina Sergeevna
- Maslivets Andrej Nikolaevich
|
RU2383549C1 |
| METHYL 3-AROYL-1-(1,5-DIMETHYL-3-OXO-2-PHENYL-2,3-DIHYDRO-1H-PYRAZOL-4-YL)-4-HYDROXY-5-OXO-2-CHLORO-2,5-DIHYDRO-1H-PYRROLE-2-CARBOXYLATES EXHIBITING ANTIMICROBIAL ACTIVITY, AND A METHOD FOR THEIR PREPARATION |
2022 |
- Denislamova Ekaterina Sergeevna
- Liadov Vadim Aleksandrovich
- Makrushin Dmitrii Evgenevich
- Maslivets Andrei Nikolaevich
- Balandina Svetlana Iurevna
|
RU2792621C1 |
| (1Z,3Z)-4-ARYL-4-HYDROXY-1-(3,3-DIALKYL-3,4-DIHYDROISOQUINOLIN-1(2N)-YLIDENE)-BUT-3-EN-4-ONES AND METHOD OF PRODUCING SAID COMPOUNDS |
2008 |
- Khalturina Valerija Vladislavovna
- Shkljaev Jurij Vladimirovich
- Maslivets Andrej Nikolaevich
- Makhmudov Ramiz Ragipovich
|
RU2374231C1 |
