METHOD TO MODEL CONDITION OF INHIBITION OF FUNCTIONAL ACTIVITY OF GLYCOPROTEIN-P BY LYNESTRENOL IN TRIAL Russian patent published in 2015 - IPC G09B23/28 

Abstract RU 2553362 C1

FIELD: pharmacology.

SUBSTANCE: during the trial rabbits are given the inhibitor preparation lynestrenol in vivo endogastrically with the daily dose of 110 mkg/kg of animal body weight in the course of 14, 21 or 28 days.

EFFECT: invention makes it possible to use lynestrenol as positive control of lower activity of glycoprotein-P for prediction of inclusion of studied medicinal agents into substrates of a transporter protein.

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RU 2 553 362 C1

Authors

Kotljarova Anna Anatol'Evna

Jakusheva Elena Nikolaevna

Dates

2015-06-10Published

2014-01-09Filed