FIELD: pharmaceutics.
SUBSTANCE: invention relates to pharmaceutical industry, specifically to use of polysaccharide hydrolyzate tansy habitus as a transporter protein inhibitor glycoprotein-P. Application of hydrolyzate of polysaccharide complex of flowers tansy with a molecular weight of 3.8 kDa, produced method for acid hydrolysis of tansy flowers with 0.1 M sulfuric acid for 3 hours, as a transporter protein inhibitor glycoprotein-P.
EFFECT: obtained hydrolyzate in vitro tests inhibits activity Pgp, and by severity of effect it is comparable to classic inhibitor of transporter protein verapamil.
1 cl, 1 dwg, 1 tbl
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Authors
Dates
2019-09-03—Published
2019-02-01—Filed