FIELD: medicine.
SUBSTANCE: invention aims at studying a membership of the analysed drug preparations among efflux carrier protein Pgp (glycoprotein P) substrates. That is ensured by the experimental simulation of the induction of functional activity of the same protein. Finasteride is used as an inducing preparation. The preparation is introduced into rabbits intragastrically in the form of a suspension in olive oil in a daily dose of 0.225 mg/kg of animal's body weight for 14 days.
EFFECT: creating the model; the safe method requires no expensive laboratory special equipment and materials.
1 tbl
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