PHARMACEUTICAL COMPOUNDS Russian patent published in 2015 - IPC C07D239/02 A61K31/4164 A61P3/00 

Abstract RU 2553451 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to a compound of formula: , wherein R1 represents C1-4 alkyl; R2 can be specified in C1-4-alkyl, 6-merous aryl, heteroaryl, partially or completely saturated 6-merous heterocyclyl containing 1 heteroatom N or O, C3-10-cycloalkyl, 6-merous aryl-C1-6-alkyl, heteroaryl-C1-6-alkyl or R1 and R2 together with N to which they are attached, can form a 10-merous heteroaryl or a 5-10-merous heterocyclyl group optionally containing 1 additional heteroatom specified in O, N and S, each of which can be optionally substituted, R5 is specified in H, C1-2-alkyl, halogen; R6 is specified in a 6-10-merous aryl, 6-9-merous heteroaryl containing 1-2 heteroatoms specified in O and N; R8 represents H; and to compositions for inhibiting a fatty acid amide hydrolase (FAAH) enzyme.

EFFECT: preparing new pharmaceutical compounds.

20 cl, 2 tbl

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RU 2 553 451 C2

Authors

Kiss Laslo Ehrno

Lirmont Dehvid Aleksandr

Roza Karla Patrisia Da Koshta Perejra

Guzhman De Noron'Ja Rita

Pal'Ma Pedro Nuno Leal'

Suarish Da Sil'Va Patrisiu Manuehl' Viejra Arauzhu

Beljaev Aleksandr

Dates

2015-06-20Published

2009-12-23Filed