METHOD OF OBTAINING BENZO[b][1,4]DIAZEPINE-2,4-DIONE DERIVATIVE Russian patent published in 2015 - IPC C07D243/12 

Abstract RU 2553676 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to field of organic chemistry, namely to method of obtaining compounds of formula , where each of R1, R2, R3 and R4, which can be similar or different, represents hydrogen atom or lower alkyl group, including removal of protective group (R5) from formula compound, where R5 represents benzyl group, which can be substituted by reduction in presence of reducing agent of catalytic hydrogenation. Invention also relates to intermediate compound of formula (2) or , as well as to method of its obtaining.

EFFECT: industrially efficient, simple and effective method of obtaining basic intermediate product for production of therapeutic anti-arrhythmia means is developed.

6 cl, 44 ex

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RU 2 553 676 C2

Authors

Tsudzimori Khisajuki

Taira Siniti

Jukava Khirotaka

Abe Kaoru

Dates

2015-06-20Published

2010-08-20Filed