FIELD: medicine.
SUBSTANCE: group of inventions relates to methods for the treatment or prevention of diseases, caused by the neovascularisation of the human choroid (neovascular maculopathy), as well to pharmaceutical compositions, containing as an active ingredient at least one peptide from peptides, containing an amino acid sequence, obtained from VEGF-receptor 1 protein, and possessing activity to induce cyctotoxic T-cells in the presence of antigen-presenting cells and at least one peptide from peptides, containing an amino acid sequence, obtained from VEGF-receptor 2 protein and possessing activity to induce cyctotoxic T-cells in the presence of antigen-presenting cells or polynucleotides that code them, where cells of the vascular epithelium, involved into the neovascularisation of the human choroid, express VEGFR-1 receptor protein on the surface of cells.
EFFECT: group of inventions is effective in the treatment or prevention of diseases, caused by the neovascularisation of the human choroid (neovascular maculopathy).
36 cl, 19 dwg, 1 tbl, 1 ex
| Title | Year | Author | Number |
|---|---|---|---|
| VACCINE-BASED IMMUNOTHERAPY OF CHOROIDAL NEOVASCULARISATION | 2008 |
|
RU2481118C2 |
| URLC10-DERIVED PEPTIDE AND VACCINE CONTAINING SAME | 2015 |
|
RU2700881C2 |
| FOXP3 PEPTIDE VACCINE | 2007 |
|
RU2473557C2 |
| COMBINED THERAPY OF PANCREATIC CANCER WITH USE OF ANTIGEN POLYPEPTIDE AND CHEMOTHERAPEUTIC AGENT | 2008 |
|
RU2472522C2 |
| TEM8 PEPTIDES AND VACCINES CONTAINING THEM | 2008 |
|
RU2498993C2 |
| CDCA1-DERIVED PEPTIDE AND VACCINE CONTAINING SAME | 2015 |
|
RU2699543C2 |
| MYBL2 EPITOPE PEPTIDES AND VACCINES CONTAINING THEM | 2009 |
|
RU2496787C2 |
| UBE2T PEPTIDE AND VACCINES CONTAINING THE SAME | 2013 |
|
RU2663350C2 |
| CDCA1 EPITOPE PEPTIDES AND VACCINES CONTAINING SAME | 2009 |
|
RU2502740C2 |
| TOPK PEPTIDES AND THEIR VACCINES | 2012 |
|
RU2633503C2 |
