FOXP3 PEPTIDE VACCINE Russian patent published in 2013 - IPC C07K7/06 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to biochemistry. What is presented is a peptide having an ability to induce cytotoxic T-cells wherein the peptide consists of amino acid sequences SEQ ID NO:3-5, 7-9, 12, 15-19, 22, 24, 27-30, 37, 67 or 74, what is also presented is a peptide having an ability to induce cytotoxic T-cells wherein the peptide consists of amino acid sequences SEQ ID NO:3-5, 7-9, 12, 17, 67 or 74 wherein 1 or 2 amino acids are substituted or added. What is presented is a peptide having an ability to induce cytotoxic T-cells wherein the peptide consists of amino acid sequences SEQ ID NO:15-19, 22, 24, 27-30 and 37 wherein 1 or 2 amino acids are substituted or added. What is presented is a pharmaceutical agent used for regulation of T-reg cells containing 1 or more types of said peptides. What is disclosed is a method for inducing antigen-presenting cells. What is presented is a recovered cytotoxic cell and an antigen-presenting cell. What is disclosed is a method for regulation of T-reg cells; what is also disclosed is the used of said peptides for producing a vaccine. There are presented polynucleotides coding said peptides.

EFFECT: invention enables producing the peptides used in the pharmaceutical agent for regulation of T-reg cells.

21 cl, 10 dwg, 4 tbl, 1 ex