CDCA1-DERIVED PEPTIDE AND VACCINE CONTAINING SAME Russian patent published in 2019 - IPC C07K7/06 A61K38/08 A61K35/12 A61K35/14 A61K39/395 A61K48/00 C12N5/78 C12N5/783 C12N5/10 C12N15/09 A61P35/00 

Abstract RU 2699543 C2

FIELD: medicine.

SUBSTANCE: present invention also relates to polynucleotides coding peptides, antigen-presenting cells presenting peptides, and cytotoxic T-cells aimed at peptides, as well as to methods of inducing antigen-presenting cells or CTL. Present invention also relates to compositions and pharmaceutical compositions containing them as an active ingredient. Additionally, the present invention refers to methods of treating and/or preventing a malignant tumour and/or preventing its postoperative relapse using peptides, polynucleotides, antigen-presenting cells, cytotoxic T-cells or pharmaceutical compositions according to the present invention. Methods of inducing an immune response against a malignant tumour are also provided.

EFFECT: invention relates to epitope peptides derived from CDCA1, with the ability to induce cytotoxic T-cells.

18 cl, 12 dwg, 3 tbl, 4 ex

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RU 2 699 543 C2

Authors

Tsunoda, Takuya

Osawa, Ryuji

Yamashita, Sachiko

Watanabe, Tomohisa

Dates

2019-09-06Published

2015-07-31Filed