FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to pharmaceutical industry, namely to pharmaceutical composition in form of dry, free-flowing, compressible powder, which contains (a) rapamycin and mixture of (b) hydrophobic polyoxyethylene and polyoxypropylene block-copolymer and (c) hydrophilic polyoxyethylene and polyoxypropylene block-copolymer with weight proportions b:c equal from 1:3 to 1:9.
EFFECT: invention provides increase of powder compressibility and increase of rapamycin stability and bioavailability.
15 cl, 8 ex, 5 tbl
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Authors
Dates
2015-07-27—Published
2012-12-13—Filed