FREE-FLOWING COMPRESSIBLE RAPAMYCIN POWDER AND THEREOF-BASED PHARMACEUTICAL COMPOSITION Russian patent published in 2015 - IPC A61K9/14 A61K31/439 A61K47/34 

Abstract RU 2557919 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to pharmaceutical industry, namely to pharmaceutical composition in form of dry, free-flowing, compressible powder, which contains (a) rapamycin and mixture of (b) hydrophobic polyoxyethylene and polyoxypropylene block-copolymer and (c) hydrophilic polyoxyethylene and polyoxypropylene block-copolymer with weight proportions b:c equal from 1:3 to 1:9.

EFFECT: invention provides increase of powder compressibility and increase of rapamycin stability and bioavailability.

15 cl, 8 ex, 5 tbl

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RU 2 557 919 C1

Authors

Petrzhinskij Gregorzh

Alakhov Valerij

Patel' Kisho

Dates

2015-07-27Published

2012-12-13Filed