ANTICANCER POLYMER AGENTS Russian patent published in 2011 - IPC A61K31/765 A61K31/785 A61P35/00 

Abstract RU 2432168 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to pharmaceutics, and concerns applications of amphiphilic block copolymers for treating and preventing cancer, particularly by reduced cancer cell growth and proliferation rate. Besides, the amphiphilic block copolymers can be used for blocking of platelet and fibroblast growth factor linking with related receptors on a membrane. Preferential block copolymers contain a basic hydrophobic chain, preferentially a polypropylene oxide chain whereto there are attached at least two hydrophilic side chains, preferentially a polyethylene oxide chain with mean ethylene oxide making less than 80 % of said amphiphilic block copolymer and molecular weight of the basic hydrophobic polymeric chain making at least 2000 g/mol.

EFFECT: invention provides new chemotherapeutic polymer drug for various types of cancer, having an effect of reduced cancer cell proliferation rate.

18 cl, 13 dwg, 11 tbl

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RU 2 432 168 C2

Authors

Bruse Lars

Bruse Ingrid

Dates

2011-10-27Published

2007-04-23Filed