ANTIOXIDANT AGENT OF NANOSTRUCTURED SELENIUM WITH HEPATOPROTECTIVE EFFECT AND METHODS FOR PRODUCING AND USING IT Russian patent published in 2015 - IPC A61K33/04 A61K47/36 A61P1/16 A61P39/06 B82B1/00 B82Y30/00 

Abstract RU 2557992 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to pharmaceutical industry, namely to selenium nanocomposites of natural hepatotrophic galactose-containing polysaccharide matrixes, representing water-soluble orange-red powders containing zerovalent selenium (Se0) nanoparticles sized 1-100 nm in the quantitative content of 0.5 - 60 wt %, possessing antioxidant activity for treating and preventing redox-related pathologies, particularly for treating toxic liver damage, to a method for producing and to an antioxidant agent containing the above nanocomposites.

EFFECT: invention provides the targeted agent delivery to liver cells, as well as higher agent accessibility and lower toxic action of selenium.

7 cl, 11 ex, 4 tbl

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RU 2 557 992 C1

Authors

Karpova Ekaterina Aleksandrovna

Sukhov Boris Gennad'Evich

Kolesnikova Ljubov' Il'Inichna

Vlasov Boris Jakovlevich

Il'Ina Ol'Ga Petrovna

Artem'Ev Aleksandr Viktorovich

Lesnichnaja Marina Vladimirovna

Pogodaeva Natal'Ja Nikolaevna

Sajvanova Svetlana Alekseevna

Kuznetsov Sergej Viktorovich

Trofimov Boris Aleksandrovich

Dates

2015-07-27Published

2013-12-30Filed