METHOD FOR DETECTING AND LOCALISING GLIAL BRAIN TUMOURS INTRAOPERATIVELY Russian patent published in 2015 - IPC A61N5/67 A61K31/197 A61P43/00 

Abstract RU 2561030 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to neurosurgical oncology, and can be used to detect and localise a brain tumour. A surgical intervention involves taking solution of 5-aminolevilinic acid. The tumour is removed under visual control with the use of a surgical microscope provided with a white-light source. To detect the involved brain regions, a brain region of interest is occasionally illuminated locally with laser light at wave length 405 nm. The involved region is examined simultaneously in the reflected white light and protoporphyrin IX red fluorescent light through a rejection filter lens blocking the laser light reflected from the object. Using a laser emitter at wave length in the proximity of a short-wavelength visual reception limit enables blocking the reflected laser light without loss of the white light examination.

EFFECT: method enables the more complete tumour removal in a combination with preserving functionally significant brain regions by combining the white and PPIX red fluorescent light tumour examination through the rejection filter lens blocking the laser light reflected from the object.

2 cl, 1 dwg, 1 ex

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RU 2 561 030 C1

Authors

Papajan Garri Vazgenovich

Svistov Dmitrij Vladimirovich

Martynov Boris Vladimirovich

Petrishchev Nikolaj Nikolaevich

Dates

2015-08-20Published

2014-01-30Filed