DEVICE FOR PHOTODYNAMIC THERAPY OF RESIDUAL BRAIN TUMORS WITH FLUORESCENT CONTROL OF PHOTOSENSITIZER PHOTODECOLORIZATION Russian patent published in 2023 - IPC A61N5/67 

FIELD: medicine.

SUBSTANCE: device for photodynamic therapy of residual brain tumors with fluorescent control of photosensitizer photobleaching contains a one-piece housing hermetically articulated with a latex balloon, and the shell has two independent channels, one of which is designed to deliver a light-scattering emulsion to the balloon, and the second — to deliver to the zone of photodynamic exposure therapeutic optical fiber and diagnostic optical fiber, a glass limiter for these optical fibers rigidly fixed to the body, a radiation source for photodynamic therapy associated with a therapeutic optical fiber, a radiation source for spectral fluorescence diagnostics associated with a diagnostic optical fiber, a spectroscopic module, made with the possibility of recording a fluorescent signal from a diagnostic optical fiber and connected to a personal computer with software to determine the fluorescence intensity of the photosensitizer accumulated in the diagnosed tissue area, for determining pathological foci and their localization and controlling the degree of photosensitizer photobleaching to detect residual pathological foci.

EFFECT: more reliable assessment of the depth of the spread of the tumor process due to intraoperative fluorescent diagnostics, triggering apoptosis in tumor tissue cells and increasing the completeness of tumor resorption.

5 cl, 7 dwg, 2 ex