QUATERNARY AMMONIUM COMPOUNDS BASED ON PENTAERYTHRITOL AND PYRIDOXINE DERIVATIVES WITH ANTIBACTERIAL ACTIVITY Russian patent published in 2024 - IPC C07D491/56 C07D519/00 C07D401/14 C07D401/12 A61K31/4353 A61K31/4415 A61P31/04 

Abstract RU 2811203 C1

FIELD: chemistry of organic heterocyclic compounds.

SUBSTANCE: invention relates to the new quaternary ammonium compounds based on pentaerythritol and pyridoxine derivatives of formula (I).

R1+R2=-C(CH3)2OCH2-, R3+R4= -CH2-, R5=C10H21, n=2;

R1+R2=-C(CH3)2OCH2-, R3+R4= -CH2-, R5=C12H25, n=2;

R1+R2=-C(CH3)2OCH2-, R3+R4= -CH2-, R5=C14H29, n=2;

R1=H, R2=CH2OH, R3+R4= -CH2-, R5=C10H21, n=2;

R1=H, R2=CH2OH, R3+R4= -CH2-, R5=C12H21, n=2;

R1=H, R2=CH2OH, R3+R4= -CH2-, R5=C14H25, n=2;

R1=H, R2=CH2OH, R3+R4= -CH(CH3)-, R5=C10H21, n=2;

R1=H, R2=CH2OH, R3+R4= -CH(CH3)-, R5=C12H25, n=2;

R1=H, R2=CH2OH, R3+R4= -CH(CH3)-, R5=C14H29, n=2;

R1=R3=R4=H, R2=CH2OH, R5=C10H21, n=2;

R1=R3=R4=H, R2=CH2OH, R5=C12H25, n=2;

R1=R3=R4=H, R2=CH2OH, R5=C14H29, n=2.

EFFECT: obtaining new compounds that can be used in medicine and veterinary medicine as agents exhibiting antibacterial activity.

2 cl, 3 dwg, 27 ex

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Authors

Shtyrlin Iurii Grigorevich

Sapozhnikov Sergei Vitalevich

Shtyrlin Nikita Valerevich

Biktimirova Alina Sergeevna

Bulatova Elena Sergeevna

Agafonova Mariia Nikolaevna

Dates

2024-01-11Published

2023-11-17Filed