PYRIDOXIN AND ACETONE DERIVATIVES WITH ANTITUMOR ACTIVITY Russian patent published in 2017 - IPC C07D491/56 A61K31/357 A61K31/4355 A61P35/00 

FIELD: pharmacology.

SUBSTANCE: invention relates to pyridoxine and acetone derivatives of the general formula I , where R¹=R²=CH₃; R¹=H, R²=C₂H₅; R¹=H, R²=C₃H₇; R¹=H, R²=C₄H₉; R¹-R²=spiro-C₄H₈; R¹-R²=spiro-C₅H₁₀; R¹= H, R²= CH (CH₃) C₉H₁₉.

EFFECT: these compounds have expressed antitumor activity against cells of predominantly malignant neoplasms and provide high security in relation to the conditionally normal and normal cells and high value of lethal dose LD₅₀, and may have applications in medicine.

3 dwg, 14 ex