FIELD: medicine.
SUBSTANCE: from the 6th day following Pliss lymphosarcoma transplantation, a ferric nanoparticle suspension concentrated 1 mg/ml in normal saline is administered eight times intraperitoneally or locally into the tumour in male rats. The administration is performed on the 6th, 7th, 9th, 10th, 14th, 15th, 16th and 17th days in a single dose of 1.25 mg/kg of the animal's weight.
EFFECT: method enables achieving the anticancer action of the nanoparticles having low toxic body exposure.
2 tbl
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METHOD FOR TUMOUR GROWTH INHIBITION IN EXPERIMENT | 2012 |
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RU2506971C1 |
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PREPARATION FOR INHIBITING TUMOR GROWTH AND METHOD FOR INHIBITING TUMOR GROWTH IN EXPERIMENT | 2006 |
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RU2559086C1 |
METHOD OF INCREASING EVENT-FREE DURATION OF TUMOUR-CARRIER LIFE IN EXPERIMENT | 2009 |
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RU2417942C1 |
METHOD FOR TREATING MALIGNANT NEOPLASMS UNDER EXPERIMENTAL CONDITIONS | 2003 |
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RU2261733C2 |
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RU2638448C1 |
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RU2413311C1 |
SUCROSE AND O-CHLOROBENZOIC ACID MONOESTER SHOWING ANTITUMOR ACTIVITY | 1990 |
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SU1783812A1 |
Authors
Dates
2015-08-27—Published
2014-05-08—Filed