METHOD FOR TUMOUR GROWTH INHIBITION IN EXPERIMENT Russian patent published in 2014 - IPC A61N5/02 B82B1/00 A61K31/196 A61K33/26 A61P35/00 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to experimental studies in oncology and may be used for assessing the anti-tumour action of metal nanoparticles (NP). An iron nanoparticle suspension 1.25 mg/kg is introduced into grafted Pliss lymphosarcoma intratumourally. That is followed by the paratumoural introduction of methotrexate 0.2 mg/kg. The tumour is locally heated to temperature 42-43°C using an electromagnetic UHF emission at frequency 12.7 MHz for 10 minutes. The therapy requires 5 such sessions in total every 48 hours. That is followed by calculating an effectiveness index, a complete regression percentage and Pliss lymphosarcoma growth inhibition percentage.

EFFECT: method intensifies the antitumor effect of the thermal chemotherapy without increasing body toxicity.

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