FIELD: medicine.
SUBSTANCE: invention relates to medicine, namely, to experimental research in oncology and can be used in investigation of impact of metal nanoparticles on tumour growth in vivo. For this purpose, 0.2 ml of each: suspension of nanoparticles of metals of copper, zinc or alloy Cu+Zn+Fe in concentration 10 mcg/ml are introduced to tumour-carrying mice with sarcoma 180 three weeks after transplantation. Introduction is carried out 2 times per week during 5 weeks, after that introduction of metal nanoparticles is stopped.
EFFECT: method makes it possible to ensure increase of general and event-free duration of life of tumour-carrying mice with transplanted sarcoma 180 due to high ability of metal nanoparticles to penetrate into cells and imbed into various metabolic chains.
2 tbl
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Authors
Dates
2011-05-10—Published
2009-09-25—Filed