METHOD OF INCREASING EVENT-FREE DURATION OF TUMOUR-CARRIER LIFE IN EXPERIMENT Russian patent published in 2011 - IPC B82B1/00 A61P35/00 

Abstract RU 2417942 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely, to experimental research in oncology and can be used in investigation of impact of metal nanoparticles on tumour growth in vivo. For this purpose, 0.2 ml of each: suspension of nanoparticles of metals of copper, zinc or alloy Cu+Zn+Fe in concentration 10 mcg/ml are introduced to tumour-carrying mice with sarcoma 180 three weeks after transplantation. Introduction is carried out 2 times per week during 5 weeks, after that introduction of metal nanoparticles is stopped.

EFFECT: method makes it possible to ensure increase of general and event-free duration of life of tumour-carrying mice with transplanted sarcoma 180 due to high ability of metal nanoparticles to penetrate into cells and imbed into various metabolic chains.

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RU 2 417 942 C1

Authors

Sidorenko Jurij Sergeevich

Zlatnik Elena Jur'Evna

Peredreeva Larisa Viktorovna

Borodulin Vladimir Borisovich

Zhornikova Natal'Ja Aleksandrovna

Dates

2011-05-10Published

2009-09-25Filed