METHOD FOR SIMULATING COMBINED EXPOSURE TO DEPLETED URANIUM Russian patent published in 2015 - IPC G09B23/28 

FIELD: medicine.

SUBSTANCE: simulating the acute exposure to depleted uranium in anaesthetised rats is ensured by single series administration of various forms of uranium. Uranium is administered as mixed uranium oxide (U₃O₈) dust into the lungs in an element dose range of 1 to 100 mg ²³⁸U/kg of body weight. The intragastric administration of hexavalent uranium salt dissolved in deionised water also follows the element dose range of 1 to 100 mg ²³⁸U/kg of body weight. Uranium is also administered as skin applications by immersing an animal's tail by two thirds into uranium solution 0.5 g/l for 10-60 minutes.

EFFECT: method reproduces the acute combined exposure to depleted uranium close to that in humans in military conflicts, as well as living in endemic regions of uranium deposits and storage facilities.

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