FIELD: medicine.
SUBSTANCE: method comprises the study of ezrin expression and the process of methylation of genes in the endometrium. In case of increased expression of ezrin in cell cytoplasm from 4 to 6 points and reduction of the process of methylation of genes under the influence of O6- methylguanil-DNA of methyltransferase (MGMT) to the level of no more than 2 points the possibility is determined of malignant pathological process and occurrence of endometrioid adenocarcinoma.
EFFECT: use of invention enables to increase the efficiency of differential diagnostics and prognosis of endometrial cancer in patients of perimenopausal period.
4 dwg, 1 ex
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Authors
Dates
2015-08-27—Published
2014-06-19—Filed