TREATMENT OF OSTEOPOROSIS Russian patent published in 2015 - IPC C07C66/00 C07C69/95 A61K31/122 A61K31/216 A61P19/10 

Abstract RU 2562976 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: claimed invention relates to application of formula

compound, or its pharmaceutically acceptable salt, or its N-acyl derivative, or its Mannich base for treatment of osteoporosis and/or osteopenia, as well as to pharmaceutical composition, pharmaceutical preparation, combined product and versions of set, including formula (I) compound. In addition invention relates to application of formula (I) compound or pharmaceutical composition which contains it for preparation of medication, as well as to method of treating osteoporosis and/or osteopenia. In formula (I) R1 represents alkyl group, including alkyl group with non-branched or branched chain, containing from 1 to 9 carbon atoms; R2 represents hydrogen; R3 is represented by the following formula (II):

,

where unconnected bond represents point of binding of structural fragment of formula (II) to residue of for formula (I) compound. Ra, Rc, Rd, Re, r, s, and n have values, given in invention formula.

EFFECT: obtaining compounds for treatment of osteoporosis and/or osteopenia.

22 cl, 20 dwg, 4 ex

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RU 2 562 976 C2

Authors

Khodzhes Stiven

Soper Robin

Dates

2015-09-10Published

2010-12-22Filed