FIELD: medicine.
SUBSTANCE: invention relates to medicine, namely to neurology, and can be used for treatment of partial epileptic seizures. For this purpose cannabidiol (CBD) is administered to patient in form of isolated compound or vegetable extract in amount, providing day dose of at least 400 mg. Vegetable extract contains less than 5 wt % of tetrahydrocannabinole (THC) as percentage of any cannabinoids, present in mixture composition. Application of CBD in combination with tetrahydrocannabivarin (THCV), where THCV is present in amount, providing day dose of at least 1.5 mg, is also claimed.
EFFECT: invention makes it possible to use phytocannabinoids in effective dose for treatment of certain forms of epilepsy-associated seizures.
11 cl, 3 tbl, 20 dwg, 6 ex
| Title | Year | Author | Number |
|---|---|---|---|
| USING CANNABINOIDS COMBINED WITH ANTIPSYCHOTIC DRUG PREPARATION | 2008 |
|
RU2503448C2 |
| PHARMACEUTICAL DRUG | 2019 |
|
RU2795027C2 |
| METHOD OF DETECTING ANTICONVULSANT ACTION OF SODIUM CITICOLINE AND VALPROATE WHEN APPLYING THEM TOGETHER ON MODEL OF ACUTE GENERALIZED CONVULSIONS CAUSED BY PENTYLENETETRAZOLE IN WISTAR MALE RATS | 2015 |
|
RU2600477C1 |
| 4-BENZOYLPYRIDINE OXIME DERIVATIVES HAVING ANTICONVULSANT ACTIVITY AS AGENTS FOR TREATMENT OF EPILEPSY AND PAROXYSMAL STATES | 2016 |
|
RU2643091C2 |
| ANTICONVULSANT AND ANTIHYPOXIC AGENT | 2008 |
|
RU2393857C2 |
| PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING PAROXYSMAL CONDITIONS | 2011 |
|
RU2469722C1 |
| APPLICATION OF VINPOCETINE FOR PREVENTION OF COMPLICATIONS, IN PARTICULAR HEARING-RELATED COMPLICATIONS, ACCOMPANYING EPILEPSY AND ITS TREATMENT | 2003 |
|
RU2376990C2 |
| METHOD OF CHILDREN ABSENTIA TREATMENT ASSOCIATED WITH IDIOPATHIC GENERALISED EPILEPSY | 2005 |
|
RU2329761C2 |
| DERIVATIVES OF 4-PHENYLPYRROLIDONE WITH ANTICONVULSANT AND NOOTROPIC ACTIVITY AS MEANS OF TREATING EPILEPSY AND PAROXYSMAL CONDITIONS | 2017 |
|
RU2748419C2 |
| N-ALKYL-TROPINES AND N-ALKYL-NORTROPINES HAVING h-LYTIC, ANTIPARKINSONIAN, ANTIEPILEPTIC, ANALGESIC AND ANTIDEPRESSANT ACTIVITY | 2014 |
|
RU2597616C2 |
