FIELD: chemistry.
SUBSTANCE: invention relates to a method for synthesis of substituted meta-terphenyls - (aryl)[5'-(methylamino)-2'-nitro-1,1':3',1"-terphenyl-4'-yl]methanones of general formula I, which can be used in organic synthesis and in production of biologically active substances, including medicinal drugs. The method includes subjecting quaternary salts of 4-aryl-3-aroyl-1,2-dimethyl-5-nitro-6-phenylpyridinium of general formula II to regrouping under the effect of 40% aqueous methylamine into substituted meta-terphenyls of general formula I. In formulae I and II, R=H, OMe; X=Me, OMe, Cl, Br; in formula II when R=H, A-=MeOSO3; when R=OMe, A-=ClO4.
EFFECT: method enables to obtain desired products with high output.
36 ex
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Authors
Dates
2015-09-20—Published
2014-10-14—Filed