METHOD FOR PRODUCING N,N-COMPLEXES OF DICHLORODI-[3,5-DIMETHYL-4-(SULFANYLMETHYL)-1H-PYRAZOLE]COPPER DIHYDRATE (II) Russian patent published in 2019 - IPC C07F1/08 A61K31/555 B01J31/22 

Abstract RU 2677484 C2

FIELD: chemistry.

SUBSTANCE: invention relates to the field of the chemistry of coordination compounds, in particular to a process of the producing of N,N-complexes of dichlorodi-[3,5-dimethyl-4-(sulfonylmethyl)-1H-pyrazole]dihydrate copper (II) (1):

. Method comprises reacting bidentate reagents of C-thiomethylated 3,5-dimethyl-4-(sulfanylmethyl)-1H-pyrazole with copper (II) chloride dihydrate, in acetonitrile medium with a molar ratio copper (II) chloride dihydrate : 3,5-dimethyl-4-(sulfanylmethyl)-1H-pyrazole, equal to 1:2, at temperature of 15–30 °C and atmospheric pressure for 3–5 hours.

EFFECT: obtained compounds can be used as biologically active substances with antioxidant and anticancer activity, as well as catalysts for chemical reactions.

1 cl, 1 tbl, 1 ex

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RU 2 677 484 C2

Authors

Akhmetova Vnira Rakhimovna

Akhmadiev Nail Salavatovich

Nurtdinova Galiya Maratovna

Khisamutdinov Ravil Akhmetzyanovich

Ibragimov Askhat Gabdrakhmanovich

Dzhemilev Usein Memetovich

Dates

2019-01-17Published

2017-03-23Filed