FIELD: chemistry.
SUBSTANCE: invention relates to a method of producing methyl 3-acyl-4-cyano-5-(dicyanomethylene)-2-hydroxy-2,5-dihydro-1H-pyrrole-2-carboxylates of general formula (A)
,
where R = 2-furyl (A1), 2-thiophenyl (A2), 3,4-(MeO)2-C6H3 (A3), 3-NO2-C6H4 (A4), 4-Br-C6H4 (A5), styryl (A6). Method includes adding to a suspension of tetracyanoethylene in a mixture of benzene - diethyl ether (4:1) methyl 2,4-dioxo-4-R-butanoate, stirring at room temperature until complete dissolution, holding at temperature 0–5 °C for 30–40 h, filtration of precipitate and its washing with cooled diethyl ether.
EFFECT: invention simplifies the method of producing compounds of general formula (A).
1 cl, 6 ex
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Year |
Author |
Number |
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|
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