1-(2-FLUOROBIPHENYL-4-YL)-ALKYLCARBOXYLIC ACID DERIVATIVES FOR TREATING TRANSTHYRETIN AMYLOIDOSIS Russian patent published in 2015 - IPC C07C57/58 A61K31/19 A61P25/28 A61P43/00 

Abstract RU 2565066 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to using 1-(2-fluorobiphenyl-4-yl)-alkylcarboxylic acid derivatives as agents able to stabilise the tetramer native condition of transthyretin for preventing and treating amyloidosis.

EFFECT: producing the agent for preventing and treating amyloidosis.

10 cl, 1 ex

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RU 2 565 066 C2

Authors

Imbimbo Bruno P'Etro

Villetti Dzhino

Berni Rodol'Fo

Dates

2015-10-20Published

2011-04-19Filed