CRYSTALLINE SOLID FORMS OF 6-CARBOXY-2-(3,5-DICHLOROPHENYL)BENZOXAZOLE Russian patent published in 2019 - IPC C07D263/57 A61K31/423 A61P25/00 

Abstract RU 2692252 C2

FIELD: medicine; pharmaceuticals.

SUBSTANCE: invention relates to crystalline form of 6-carboxy-2-(3,5-dichlorophenyl)benzoxazole, as well as to pharmaceutical compositions based thereon for treating transthyretin-amyloid disease.

EFFECT: technical result: obtaining a novel crystalline form, having higher stability, improved solubility, gel formation.

15 cl, 5 ex, 1 tbl, 21 dwg

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RU 2 692 252 C2

Authors

Girard, Kevin Paul

Jensen, Andrew J.

Jones, Kris Nicole

Dates

2019-06-24Published

2015-08-31Filed