FIELD: chemistry.
SUBSTANCE: invention relates to three-dimensional bioplastic material, which includes base in form of matrix, for which hydrocolloid of hyaluronic acid is used as material. Framework for said bioconstruction results from combination of gel-electrophoresis and low-temperature lyophilic drying methods with obtaining layered three-dimensional structure, external-dense, homogeneous, internal - porous with multitude of heterogeneous voids with size 252.16 ± 98.73 mcm, with said structure being preserved under conditions of cell cultivation in vitro and experiment in vivo.
EFFECT: invention provides increase of wound healing effectiveness and represents base for elaboration of novel tissue-engineered constructions and artificial organs.
16 dwg, 1 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| COSMETIC SKIN | 2013 |
|
RU2528899C1 |
| BIOLOGICALLY ACTIVE MATERIAL FOR COVERING WOUND SURFACES | 2022 |
|
RU2804197C1 |
| METHOD FOR PRODUCTION OF COLLAGEN-LAMININ MATRIX FOR HEALING OF ULCERS, BURNS AND WOUNDS OF HUMAN SKIN | 2018 |
|
RU2736480C2 |
| BACTERICIDAL ANTI-BURN BIODEGRADABLE AGENT BASED ON A COLLAGEN PHARMACEUTICAL COMPOSITION WITH LACTOFERRIN, METHODS OF PRODUCING (VERSIONS) AND PROPERTIES | 2019 |
|
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| METHOD FOR TREATMENT OF UNINFECTED POSTOPERATIVE WOUND DEFECT OF THE FOOT IN THE ABSENCE OF SIGNS OF CRITICAL LIMB ISCHEMIA IN PATIENTS WITH NEUROPATHIC AND NEUROISCHEMIC FORMS OF DIABETIC FOOT SYNDROME | 2020 |
|
RU2754383C1 |
| ANTI-BURN AGENT BASED ON ASPEN LEAVES, FLOWERS OF CALENDULA, WILD CAMOMILE | 2016 |
|
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| HISTO-EQUIVALENT BIOPLASTIC MATERIAL | 2013 |
|
RU2513838C1 |
| BIORESORBABLE MICRO-CARRIER FOR CELL DELIVERY TO REGION OF WOUND HEALING AND REGENERATION | 2015 |
|
RU2616866C1 |
| BIOPLASTIC MATERIAL | 2008 |
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| METHOD OF FORMATION OF THREE-DIMENSIONAL BIORESORBABLE STRUCTURES | 2017 |
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RU2691752C1 |
