FIELD: medicine.
SUBSTANCE: invention refers to the new uracil derivative 1,3-bis[5-(orto-nitrobenzyl-ethylamino)pentyl-1]-6-methyluracil described by structural formula presented below. The compound is applicable in therapy of Alzheimer disease. Presented are anticholinesterase activity indices of the compound, its general toxic action and findings obtained in a scopolamine and genetic model in the therapy of symptoms of Alzheimer disease.
EFFECT: higher clinical effectiveness ensured by the above agent.
2 cl, 5 tbl, 6 ex
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Authors
Dates
2015-10-20—Published
2014-12-22—Filed