X-VISUALISATION AT LOW CONCENTRATIONS OF CONTRAST AGENT AND/OR LOW DOSE OF RADIATION Russian patent published in 2015 - IPC A61K49/04 A61K49/08 A61K51/02 A61K101/02 

FIELD: medicine.

SUBSTANCE: invention relates to field of medicine, namely to X-ray diagnostic composition, containing iodised radiopaque agent and pharmaceutically acceptable carrier or excipient, where concentration of iodine in composition constitutes from 10 to less than 100 mg I/ml and where radiopaque agent represents formula II compound: and to method of X-ray examination, which includes introduction of said composition into organism, exposure of organism to X-ray radiation dose, provided at energy of tube voltage in the range 70-140 kVp; examination of organism with application of diagnostic device, and compilation of examination data; additionally including stage of noise suppression by method of improved image reconstruction.

EFFECT: invention provides reduction of impact of ionising radiation and iodine concentration in composition to low levels with preservation of quality of obtained X-ray image.

8 cl, 7 ex, 4 tbl, 16 dwg