METHOD OF OBTAINING OF 4-(7-CYCLOHEPTA-1,3,5-TRIENYL)ANILINE AND ITS HYDROCHLORIDE, DEMONSTRATING ANTIMICROBIAL ACTIVITY Russian patent published in 2015 - IPC C07C211/45 C07C209/52 C07C209/68 A61P31/04 

Abstract RU 2568641 C2

FIELD: medicine.

SUBSTANCE: method consists in tropylation of N-benzylidenaniline with tropylium tetrafluoroborate for 3-18 hours, with further neutralisation of obtained compound to obtain N-benzyliden-4-(7-cyclohepta-1,3,5-trienyl)aniline, which is hydrolised with hydrochloric acid in benzene medium, obtained hydrochloride is processed with base. Method is realised in accordance with the following scheme: 1 stage

2 stage 3 stage Method makes it possible to obtain product with high output and simplify process due to elimination of toxic and explosive substances Method can be used on an industrial scale.

EFFECT: compound possesses antimicrobial activity and is low-toxic compound.

3 ex

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RU 2 568 641 C2

Authors

Junnikova Lidija Petrovna

Akent'Eva Tat'Jana Anatol'Evna

Aleksandrova Galina Arsent'Evna

Nikonov Georgij Nikolaevich

Dates

2015-11-20Published

2013-12-26Filed