FIELD: medicine.
SUBSTANCE: method consists in tropylation of N-benzylidenaniline with tropylium tetrafluoroborate for 3-18 hours, with further neutralisation of obtained compound to obtain N-benzyliden-4-(7-cyclohepta-1,3,5-trienyl)aniline, which is hydrolised with hydrochloric acid in benzene medium, obtained hydrochloride is processed with base. Method is realised in accordance with the following scheme: 1 stage
2 stage 3 stage Method makes it possible to obtain product with high output and simplify process due to elimination of toxic and explosive substances Method can be used on an industrial scale.
EFFECT: compound possesses antimicrobial activity and is low-toxic compound.
3 ex
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Authors
Dates
2015-11-20—Published
2013-12-26—Filed