SULPHATED DERIVATIVES OF OLIGOSACCHARIDES Russian patent published in 2010 - IPC C07H3/06 C07H11/00 A61K31/7016 A61K31/702 A61P7/02 A61P31/22 

FIELD: chemistry.

SUBSTANCE: invention refers to sulphated oligosaccharides of the general formula X-[Y]_n-Z-UR¹, where X, Y and Z each are the same hexose monosaccharide fragment selected out of group including glucose, mannose, altrose, allose, talose, galactose, idose and gulose, adjoining monosaccharide fragments are bound in 1→2, 1→3, 1→4, and/or 1→6 pattern by glycoside bonds, and each carbon atom not binding X, Y and Z groups is bound by single bond with UR group, with exception for carbon atom in 1 position of Z monosaccharide, to which UR¹ group is bound by single bond; where n is an integer within 0 to 6; U is O atom or NH; each R is independently C₂-C₆-alkenyl, benzyl, SO₃M or H, where M is any pharmaceutically acceptable cation of alkali metal or organic amine, or R form N₃ together with U; R¹ is C₁-C₁₂alkyl, benzyl, PEG monomethyl ether or its derivative, C₁-C₁₂alkylazide, , or , in the form of ester, free acid, free base or hydrate. Also invention refers to pharmaceutical or veterinary composition based on claimed compounds, for disorder prevention or treatment for mammals in case of proliferate retinopathy, solid tumour and/or metastasis result, coagulation/thrombosis and/or virus infection of organism. Additionally invention refers to application of claimed compounds in medicine production for disorder prevention or treatment for mammals in case of proliferate retinopathy, solid tumour and/or metastasis result, coagulation/thrombosis and/or virus infection of organism.

EFFECT: increased efficiency of compound application in medicine.

11 cl, 3 tbl, 1 dwg, 16 ex