AGONISTS OF 5-HT4-RECEPTORS FOR TREATING DEMENTIA Russian patent published in 2015 - IPC A61K31/454 A61P25/28

Abstract RU 2569733 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: claimed group of inventions relates to medicine, namely to neurology, and deals with treating dementia. For this purpose an effective amount of a compound, possessing the activity of an agonist of 5-HT4-receptors - N-((1-((4-hydroxytetrahydro-2H-pyran-4-yl)methyl)piperidin-4-yl)methyl)-3-isopropyl-2-oxo-2,3-dihydro-1H-benzo[d]imodazole-1-carboxamide is introduced.

EFFECT: medication provides an improvement of the cognitive function and the reduction of the level of the beta-amyloid peptide in case of neurodegenerative diseases.

9 cl, 4 ex, 4 dwg

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RU 2 569 733 C2

Authors

Okhsiro Khirojuki

Fudzijuti Akiesi

Take Jukinori

Dates

2015-11-27—Published

2011-02-14—Filed