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2 570 380

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IPC

A61K31/4178(2006-01-01)

A61K9/51(2006-01-01)

A61K47/36(2006-01-01)

A61J3/07(2006-01-01)

B82B3/00(2006-01-01)

(21) (22)

Application

2014112486/15, 2014-03-31

(24)

Start date

2014-03-31

(22)

Actual filing date

2014-03-31

(45)

Published

2015-12-10

(72)

Inventor

Krolevets Aleksandr AleksandrovichPokrovskij Mikhail VladimirovichBogachev Il'Ja AleksandrovichJakushev Vladimir IvanovichGudyrev Oleg SergeevichRemizov Pavel PavlovichSobolev Mikhail Sergeevich

(73)

Holder

Krolevets Aleksandr AleksandrovichPokrovskij Mikhail VladimirovichBogachev Il'Ja AleksandrovichJakushev Vladimir IvanovichGudyrev Oleg SergeevichRemizov Pavel PavlovichSobolev Mikhail Sergeevich

METHOD FOR OBTAINING LOSARTAN POTASSIUM NANOCAPSULES IN XANTHAN GUM Russian patent published in 2015 - IPC A61K31/4178 A61K9/51 A61K47/36 A61J3/07 B82B3/00

Abstract RU 2570380 C2

FIELD: chemistry.

SUBSTANCE: invention relates to method for obtaining losartan potassium nanocapsules in xanthan gum. Claimed method consists in the following: losartan potassium is dissolved in chloroform and obtained mixture is dispersed into xanthan gum suspension in benzene in presence of preparation E472c with mixing, after that acetone and water are poured in, obtained suspension is filtered and dried, with envelope/core ratio in nanocapsules constituting 3:1 or 1:5.

EFFECT: invention provides simplification and acceleration of the process of obtaining losartan potassium nanocapsules, as well as increase of their output by weight.

1 dwg, 1 tbl, 3 ex

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RU 2 570 380 C2

Authors

Krolevets Aleksandr Aleksandrovich

Pokrovskij Mikhail Vladimirovich

Bogachev Il'Ja Aleksandrovich

Jakushev Vladimir Ivanovich

Gudyrev Oleg Sergeevich

Remizov Pavel Pavlovich

Sobolev Mikhail Sergeevich

Dates

2015-12-10—Published

2014-03-31—Filed