METHOD OF PRODUCTION OF MICROCAPSULES OF POTASSIUM LOSARTAN IN SODIUM ALGINATE Russian patent published in 2015 - IPC A61K31/41 A61K47/36 A61K9/50 A61J3/07 B01J13/02 

Abstract RU 2558855 C1

FIELD: biotechnologies.

SUBSTANCE: potassium losartan is dissolved in chloroform and the produced mix is dispersed in presence of the preparation E472c with mixing 1000 rpm/sec into sodium alginate suspension in benzene. Then acetone and water are added, the produced suspension is filtered and dried at the room temperature. The ratio nucleus:shell is 3:1 or 1:5, the process of obtaining of microcapsules is performed within 10 minutes.

EFFECT: simplification and acceleration of production of microcapsules of amino acids with increase of yield of ready-made product.

1 dwg, 3 ex

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RU 2 558 855 C1

Authors

Krolevets Aleksandr Aleksandrovich

Pokrovskij Mikhail Vladimirovich

Bogachev Il'Ja Aleksandrovich

Jakushev Vladimir Ivanovich

Gudyrev Oleg Sergeevich

Remizov Pavel Pavlovich

Sobolev Mikhail Sergeevich

Dates

2015-08-10Published

2014-04-15Filed