METHOD OF HYDROGENATING ISO-ALPHA-ACIDS AND TETRAHYDRO-ISO-ALPHA-ACIDS INTO HEXAHYDRO-ISO-ALPHA-ACIDS Russian patent published in 2015 - IPC C12C3/12 C07C45/62 C07C45/78 C07C45/64 B01J23/46 B01J23/38 

FIELD: chemistry.

SUBSTANCE: invention relates to a method of producing hexahydro-iso-alpha-acids from iso-alpha-acids (or tetrahydro-iso-alpha-acids), which includes mixing iso-alpha-acids (or tetrahydro-iso-alpha-acids) with a heterogeneous ruthenium-containing catalyst, which catalyses hydrogenation of iso-alpha-acids or tetrahydro-iso-alpha-acids to obtain hexahydro-iso-alpha-acids, in the absence of a solvent or in the presence of a solvent phase (e.g., carbon dioxide, water, ethanol or other organic solvent or mixtures thereof) and in the absence or in the presence of other hop compounds (such as beta-acids). The obtained mixture is then exposed to a temperature at which the reaction medium, which contains an iso-alpha-acid (or tetrahydro-iso-alpha-acid), has a sufficiently low viscosity to be easily mixed with the heterogeneous ruthenium-containing catalyst, and held in an atmosphere containing hydrogen over a reaction time sufficient for efficient conversion of the reactant, which is an iso-alpha-acid (or tetrahydro-iso-alpha-acid), into a hexahydro-iso-alpha-acid.

EFFECT: methods enable to obtain end products with high selectivity and without using an extra reduction step using an inorganic reducing agent.

21 cl, 2 dwg, 10 tbl, 11 ex