NOVEL COMPOUNDS AND COMPOSITIONS FOR TARGETING AT MALIGNANT STEM CELLS Russian patent published in 2015 - IPC C07D307/92 A61K31/343 A61P35/00 

Abstract RU 2571661 C2

FIELD: chemistry.

SUBSTANCE: invention relates to polymorphs, namely to polymorph 2-acetyl-4H,9H-naphto [2,3-b]furane-4,9-dione, characterised by X-ray diffraction pattern, in fact similar to the one on fig.2, and polymorph of 2-acetyl-4H,9H-naphto [2,3-b]furane-4,9-dione, characterised by X-ray diffraction pattern, in fact similar to the one, given on fig. 3, naphthofurane compounds in form of particles, pharmaceutical compositions for treating cancer, containing one or several naphthofurane compounds, purified compositions for treating cancer, containing one or several said naphthofurane polymorphs in form of particles, methods for obtaining said naphthofurane polymorphs, method for treating cancer in subjects requiring it and method for prolongation of progression-free survival (PFS) in patient with cancer with application of said naphthofurane compounds.

EFFECT: increased efficiency of application of compounds.

36 cl, 25 dwg, 12 tbl, 16 ex

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RU 2 571 661 C2

Authors

Li Chian Tszja

Ledzhett Dehvid

Li Juchzhi

Li Vehj

Dates

2015-12-20Published

2011-03-21Filed