METHOD OF TREATING ABDOMINAL SEPSIS OF BILE ORIGIN, COMPLICATED BY COAGULOPATHY Russian patent published in 2012 - IPC A61B17/00 A61M27/00 A61K33/14 A61P41/00 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to surgery, and can be used in treatment of patients with abdominal sepsis of peritoneal origin, complicated by coagulopathy. For this purpose performed is laparotomy with intraoperational introduction of double-lumen nasogastric probe into small intestine lumen below Treitz ligament) for active aspiration of intestinal contents. After that, sodium hypochlorite solution is introduced into abdominal cavity once and wound edges are sutured tightly to drainages. Immediately after that, intravenous infusion and intestinal dialysis with application of sodium hypochlorite are performed. 0.04% solution of sodium hypochlorite is used for sanitisation of abdominal cavity through drainage tubes and for intravenous infusions, 0.06% solution being used for intestinal dialysis. In post-operative period sanitisation of abdominal cavity, intestinal dialysis and intravenous infusions with sodium hypochlorite are performed one time per day during 1-3 days in dose 15 ml/kg.

EFFECT: method ensures efficient treatment of said pathology, and makes it possible to reduce manifestations of inflammatory reaction, as well as to prevent further development of coagulopathy due to considerable reduction of level of platelet aggregation as a result of activation of all links of coagulation link of hemostasis with sodium hypochlorite with specific sequence of actions.

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