NEW OCTAHYDROTHIENOQUINOLINE DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING DERIVATIVE, AND USING THEM Russian patent published in 2016 - IPC C07D495/04 A61K31/4365 A61K31/444 A61K31/496 A61P25/16

Abstract RU 2573399 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to compounds presented by general formula (I) and their pharmaceutically acceptable salts. The compounds of the invention possess activity of D₂receptor agonist. In general formula (I) R¹ represents a cyano group; each R² and R³ independently represents a hydrogen atom, C_1-6alkyl group, C_1-7acyl group or (C_1-6alkoxy)-C(O)-; R⁴ represents a hydrogen atom, C_1-6alkyl group or halogen-C_1-6alkyl group; the other radicals are presented in the patent claim. The invention also refers to individual compounds and pharmaceutical compositions containing an effective amount of the compound of the invention.

EFFECT: produced are the new compounds possessing the activity of D₂receptor agonist.

14 cl, 14 tbl, 433 ex

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RU 2 573 399 C2

Authors

Nisimura Tosikhiro

Teranisi Khirotaka

Josida Masako

Ueno Jasunori

Kasai Kijosi

Dates

2016-01-20—Published

2012-03-12—Filed