STEM CELL PRODUCED FROM HUMAN MONOCYTE AND USED FOR THERAPEUTIC APPLICATION AND METHOD FOR INDUCING IT Russian patent published in 2016 - IPC C12N5/78 A61P43/00 

Abstract RU 2573906 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to biotechnology. There are presented stem cells produced by culturing human monocytes in the presence of (i) M-CSF in the concentration of 5 to 100 ng/ml and (ii) at least one representative specified in a group consisting of ganglioside in the concentration of 1 to 100 mcg/ml and a water-soluble herbal extract produced by Folch extraction, in the concentration from 0.1 to 100 mcg/ml, thereby differentiating monocytes, wherein the expression of CSCR4 gene of the above stem cells is more than three or four times as much as the expression by the stem cells produced by culturing human monocytes in the presence of M-CSF and IL-3, and the expression of CSCR4 gene of the above stem cells is more than two or three times as much as the expression by mesenchymal stem cells taken from bone marrow, for treating the diseases associated with cell damages, tissue or organ damages.

EFFECT: there are presented stem cells produced by culturing human monocytes.

15 cl, 7 dwg, 3 tbl, 2 ex

Similar patents RU2573906C2

Title Year Author Number
COMPOSITION PRODUCED FROM IN VITRO CULTURE OF DEDIFFERENTIATED NON-ACTIVATED CELLS OF LIGNUM VITAE, ITS APPLICATION FOR SKIN AGEING AND DERMATITIS TREATMENT AND SKIN HEALING, AND ITS PRODUCTION METHOD 2011
  • Stjuart Nikolja
  • Mando Anna
  • Kasteks-Rizzi Natali
RU2559579C2
DEDIFFERENTIATED PROGRAMMED STEM CELLS OF MONOCYTIC ORIGIN, THEIR OBTAINING AND APPLICATION 2003
  • Kremer Bernd Karl Fridrikh
  • Fendrikh Fred
  • Runke Maren
RU2333243C2
COSMETIC APPLICATION OF DEDIFFERENTIATED PLANT CELLS 2013
  • Pari Marilin
  • Ratman Zhosseran Mishel
  • Martin Rishar
  • Lavo Brizhitt
  • Iler Paskal
RU2636518C2
PURIFIED CYANOBACTERIAE COMPONENT AND METHOD OF APPLICATION 2006
  • Jensen Gitte
  • Drapo Kristian
RU2417093C2
METHOD FOR ISOLATION OF PLURIPOTENT STEM CELLS FROM UMBILICAL BLOOD EXPRESSING ZNF281 2010
  • Kang Kiung Sun
  • Rokh Kioung Khvan
RU2511417C2
METHOD OF MODIFICATION OF PERIPHERAL BLOOD MONOCYTES TO INCREASE THEIR PARACRINE ACTIVITY DURING AUTOLOGOUS TRANSPLANTATION 2012
  • Sazonov Aleksej Ehduardovich
  • Jur'Eva Ksenija Sergeevna
  • Khvorilova Ksenija Vladimirovna
  • Kremer Elena Ehduardovna
  • Ikkert Ol'Ga Pavlovna
  • Saltykova Irina Vladimirovna
RU2497947C1
DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS 2008
  • Rezania Alireza
RU2465323C2
METHOD FOR INDUCING STEM CELL MIGRATION IN FATTY TISSUE 2010
  • Ra,Chon,Chan
  • Kan,Son,Kyn
  • Behk,Son,Chin
RU2527182C2
COMPOSITION AND METHOD FOR ELEVATING AMOUNT OF STEM CELLS AND/OR HEMOPOIETIC CELL-PRECURSORS IN CIRCULATION IN PERIPHERAL BLOOD OF MAMMALS 2001
  • Ferro Laura
  • Porta Roberto
  • Jakobelli Massimo
  • Dzhanni Alessandro Massimo
  • Stella Karmelo Karlo
RU2248216C2
HUMANISED MOUSE M-CSF 2012
  • Merfi Endrju Dzh.
  • Stivens Shon
  • Ratinam Chozhavendan
  • Ejnon Elizabet
  • Mants Markus
  • Flavell Richard
  • Jankopulos Dzhordzh D.
RU2577978C2

RU 2 573 906 C2

Authors

Khirano Khisanobu

Okhkubo Jasusi

Sasaki Kendziro

Isijama Khironobu

Dates

2016-01-27Published

2009-11-19Filed