FIELD: medicine.
SUBSTANCE: invention refers to molecular biology, biochemistry and medicine. What is presented is a composition for inducing stem cell migration in fatty tissue of adults which contains human mesenchymal stem cells from a fatty tissue of adults in an amount of 1x107 to 1x1010 as an active ingredient which express a chemokine or growth factor receptor on a cell surface, or a secretory product of the above stem cells contain the chemokine or growth factor receptor; wherein the secretory product of the stem cells of the fatty tissue of adults represents adiponectin; and wherein the human stem cells of the fatty tissue of adults are first treated with a mixture containing chemokine or growth factor.
EFFECT: invention can be used in medicine as a cell therapeutic agent for more effective stem cell migration to an affected area.
8 cl, 9 dwg, 8 tbl, 8 ex
Title | Year | Author | Number |
---|---|---|---|
METHOD FOR INCREASING ANGIOGENIC ACTIVITY OF STROMAL CELLS OF FATTY TISSUE | 2011 |
|
RU2531502C2 |
HUTC MODULATION OF PRO-INFLAMMATORY MEDIATORS OF LUNG AND PULMONARY DISEASES AND DISORDERS | 2013 |
|
RU2668389C2 |
METHOD FOR ISOLATION OF PLURIPOTENT STEM CELLS FROM UMBILICAL BLOOD EXPRESSING ZNF281 | 2010 |
|
RU2511417C2 |
METHOD FOR TREATING FROSTBITE USING MESENCHYMAL STEM CELLS ISOLATED FROM RED BONE MARROW | 2020 |
|
RU2748539C1 |
CELL-FREE THERAPEUTIC AGENTS FOR REGENERATIVE MEDICINE AND METHODS FOR PREPARING THEM | 2018 |
|
RU2742034C2 |
METHOD OF OBTAINING EXOSOMES ORIGINING FROM MESENCHYMAL STEM CELLS AND A CULTURAL SOLUTION PRODUCED FROM THEM | 2020 |
|
RU2799432C1 |
COMPOSITIONS AND MULTI-PARAMETER ASSAYS FOR MEASURING BIOLOGICAL MEDIATORS OF PHYSIOLOGICAL HEALTH | 2007 |
|
RU2520080C2 |
TREATING PERIPHERAL VASCULAR DISEASES BY MEANS OF UMBILICAL CORD TISSUE CELLS | 2011 |
|
RU2576836C2 |
CULTURE MEDIUM FOR REJUVENATION OF STEM CELLS | 2012 |
|
RU2575106C1 |
STEM/PROGENITOR CELL RECOVERY FROM AMNIOTIC MEMBRANE OF UMBILICAL CORD | 2005 |
|
RU2416638C2 |
Authors
Dates
2014-08-27—Published
2010-10-25—Filed