METHOD OF DETERMINATION OF EFFECTIVE THERAPEUTIC DOSE OF ANTIEPILEPTIC PREPARATION AND RISK OF PROGRESS OF ADVERSE EFFECTS Russian patent published in 2016 - IPC C12Q1/68 

Abstract RU 2574204 C1

FIELD: biotechnologies.

SUBSTANCE: method includes sampling of a biological material, conducting of a polymerase chain reaction using candidate genes, the subsequent analysis of their allelic versions and, by the comparison of revealed allelic polymorphism with the data on its influence on an effective therapeutic dose and occurrence of adverse effects, estimate of the effective therapeutic dose of an antiepileptic preparation and identification of a risk of development of adverse effects.

EFFECT: invention allows determining the effective therapeutic dose and existence of risk of development of adverse effects with high accuracy.

5 cl, 5 tbl, 2 ex

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RU 2 574 204 C1

Authors

Krikova Ekaterina Vladimirovna

Burd Sergej Georgievich

Aksenova Marina Gennadievna

Dates

2016-02-10Published

2014-10-30Filed