FIELD: biotechnologies.
SUBSTANCE: method includes sampling of a biological material, conducting of a polymerase chain reaction using candidate genes, the subsequent analysis of their allelic versions and, by the comparison of revealed allelic polymorphism with the data on its influence on an effective therapeutic dose and occurrence of adverse effects, estimate of the effective therapeutic dose of an antiepileptic preparation and identification of a risk of development of adverse effects.
EFFECT: invention allows determining the effective therapeutic dose and existence of risk of development of adverse effects with high accuracy.
5 cl, 5 tbl, 2 ex
Title | Year | Author | Number |
---|---|---|---|
METHOD FOR SELECTION OF PERINDOPRIL DOSAGE FORPATIENTS WITH ISCHEMIC HEART DISEASE ON BACKGROUND OF ARTERIAL HYPERTENSION | 2016 |
|
RU2642284C1 |
METHOD OF TREATING AND/OR PREVENTION OF EXCESSIVE BODY WEIGHT AND/OR OBESITY AND/OR METABOLIC DISORDERS | 2008 |
|
RU2403038C2 |
METHOD FOR PREDICTION OF EFFECTIVENESS OF TREATMENT OF RHEUMATOID ARTHRITIS WITH DRUG OLOKIZUMAB BASED ON GENOTYPING | 2020 |
|
RU2749247C1 |
METHOD FOR PREDICTION OF CISPLATIN TREATMENT EFFICACY IN MALIGNANT DISEASE | 2014 |
|
RU2582968C2 |
METHOD FOR SELECTING THERAPEUTIC APPROACH IN PATIENTS WITH SCHIZOPHRENIA | 2022 |
|
RU2821045C1 |
METHOD FOR DETERMINING TOPIRAMATE IN BLOOD PLASMA | 2016 |
|
RU2631613C1 |
METHOD FOR PREDICTING THE DEGREE OF RISK OF EXTRAPYRAMID SIDE EFFECTS DURING THE BACKGROUND OF HALOPERIDOL THERAPY IN PATIENTS WITH SCHIZOPHRENIC SPECTRUM DISORDERS | 2021 |
|
RU2771180C1 |
METHOD FOR SELECTING SURGICAL TREATMENT VOLUME FOR THYROID DISEASES | 2020 |
|
RU2743706C1 |
METHOD OF SELECTING TREATMENT TACTICS FOR PATIENTS WITH ANTIPSYCHOTIC-INDUCED EXTRAPYRAMIDAL DISORDERS | 2022 |
|
RU2810798C1 |
METHOD FOR SELECTING THERAPEUTIC APPROACH TO AGE-RELATED MACULAR DEGENERATION (AMD) | 2018 |
|
RU2707955C1 |
Authors
Dates
2016-02-10—Published
2014-10-30—Filed