METHOD OF BOTULINUM TOXIN INJECTION INTO MASTICATORY MUSCLES Russian patent published in 2016 - IPC A61K39/02 A61P21/00 

FIELD: medicine.

SUBSTANCE: area of planned injection is determined in skin of right and left facial part of patient's head by means of thermal imager or by electromyography, after which palpation of soft tissues in the depth of the entire selected area is performed, presence and quantity of sites with higher and painful hardness are detected in it, their localisation, shape, size and volume are specified. The total single dose of botulinum toxin is diluted with solution of 0.9% sodium chloride in volume 2.5 ml in case of the total volume of sites not exceeding drug volume, with application of solution in equal volume in case of larger total volume. Solution of medication is introduced under ultrasound navigation by turns into each solid site of each muscle until its complete infiltration with solution.

EFFECT: elimination of increased tension, painfulness of masticatory muscles and recovery of chewing function under conditions, excluding impairment of facial expression, face asymmetry and impairment of chewing function.

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