FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to organic salts of Bromfenac, which are a diethylamine or trometamol salt of Bromfenac and have a structure presented by the formulas II or III below. The above salts possess good anti-inflammatory and analgesic activity, stability, and also have the improved characteristics of coetaneous penetration and tissue distribution.
EFFECT: invention also refers to a method for producing the above organic salts of Bromfenac, a pharmaceutical composition containing them, methods of treating and/or preventing an inflammation or providing analgesia with using them, as well as to using them for preparing a medicinal agent applicable for treating and/or preventing an inflammation, or providing analgesia.
23 cl, 7 tbl, 6 ex
Authors
Dates
2016-02-27—Published
2011-12-13—Filed